MSC Cruises from Palermo, Sicily, Italy

A high-angle view of the historic city of Palermo, Sicily, with a clear blue sky, buildings and rooftops in the foreground, and mountains in the distance.

Upcoming MSC Cruises from Palermo, Sicily, Italy

9 Results

Taxes and fees included in all prices shown

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Mount Vesuvius overlooking Naples Bay.

Save 35% + Kids Sail FREE*

7 nights Westmed From Palermo, Sicily, Italy

Barcelona (Tarragona)

Provence (Marseille)

Aboard

MSC Seaview

From

Palermo, Sicily, Italy

42 Sailings

Nov 2, 2026 - Jan 6, 2028

42 Sailings

Nov 2, 2026 - Jan 6, 2028

Published prices from

$820

per person*

taxes & fees included

Roman Amphitheatre of Tarragona by the sea.

Up to $500 FREE Onboard Credit*+ 2 more offers

7 nights Westmed From Palermo, Sicily, Italy

Barcelona (Tarragona)

Provence (Marseille)

Aboard

MSC Euribia

From

Palermo, Sicily, Italy

44 Sailings

Nov 4, 2026 - Mar 22, 2028

44 Sailings

Nov 4, 2026 - Mar 22, 2028

Published prices from

$720

per person*

taxes & fees included

A high-angle view of the historic city of Palermo, Sicily, with a clear blue sky, buildings and rooftops in the foreground, and mountains in the distance.

Save 35% + Kids Sail FREE*

7 nights Westmed From Palermo, Sicily, Italy

Barcelona (Tarragona)

Provence (Marseille)

Florence/Pisa (Livorno)

Aboard

MSC Splendida

From

Palermo, Sicily, Italy

1 Sailing

Nov 5, 2026

1 Sailing

Nov 5, 2026

Published prices from

$828

per person*

taxes & fees included

A high-angle view of the historic city of Palermo, Sicily, with a clear blue sky, buildings and rooftops in the foreground, and mountains in the distance.

Up to $500 FREE Onboard Credit*+ 2 more offers

20 nights South America From Palermo, Sicily, Italy

Barcelona (Tarragona)

Aboard

MSC Splendida

From

Palermo, Sicily, Italy

1 Sailing

Nov 12, 2026

1 Sailing

Nov 12, 2026

Valletta, Malta skyline with illuminated buildings at dusk.

Up to $500 FREE Onboard Credit*+ 2 more offers

21 nights South America From Palermo, Sicily, Italy

Barcelona (Tarragona)

Aboard

MSC Splendida

From

Palermo, Sicily, Italy

1 Sailing

Nov 12, 2026

1 Sailing

Nov 12, 2026

Published prices from

$4,251

per person*

taxes & fees included

A high-angle view of the historic city of Palermo, Sicily, with a clear blue sky, buildings and rooftops in the foreground, and mountains in the distance.

Up to $500 FREE Onboard Credit*+ 2 more offers

7 nights Westmed From Palermo, Sicily, Italy

Provence (Marseille)

Aboard

MSC Musica

From

Palermo, Sicily, Italy

28 Sailings

Apr 19 - Oct 25, 2027

28 Sailings

Apr 19 - Oct 25, 2027

Published prices from

$850

per person*

taxes & fees included

A high-angle view of the historic city of Palermo, Sicily, with a clear blue sky, buildings and rooftops in the foreground, and mountains in the distance.

Up to $500 FREE Onboard Credit*+ 2 more offers

7 nights Westmed From Palermo, Sicily, Italy

Florence/Pisa (Livorno)

Provence (Marseille)

Barcelona (Tarragona)

Aboard

MSC Virtuosa

From

Palermo, Sicily, Italy

29 Sailings

Apr 23 - Nov 5, 2027

29 Sailings

Apr 23 - Nov 5, 2027

Published prices from

$1,080

per person*

taxes & fees included

A scenic panoramic view of Ilhabela, Brazil, showing a long, sandy beach with turquoise water, a river flowing to the sea, and lush, green mountains under a bright blue sky.

Up to $500 FREE Onboard Credit*+ 2 more offers

22 nights Westmed From Palermo, Sicily, Italy

Florence/Pisa (Livorno)

Provence (Marseille)

Barcelona (Tarragona)

Aboard

MSC Virtuosa

From

Palermo, Sicily, Italy

1 Sailing

Nov 12, 2027

1 Sailing

Nov 12, 2027

Published prices from

$8,834

per person*

taxes & fees included

A high-angle view of the historic city of Palermo, Sicily, with a clear blue sky, buildings and rooftops in the foreground, and mountains in the distance.

Up to $500 FREE Onboard Credit*+ 2 more offers

20 nights Westmed From Palermo, Sicily, Italy

Florence/Pisa (Livorno)

Provence (Marseille)

Barcelona (Tarragona)

Aboard

MSC Virtuosa

From

Palermo, Sicily, Italy

1 Sailing

Nov 12, 2027

1 Sailing

Nov 12, 2027

*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.