MSC Cruises from Palermo, Sicily, Italy

A high-angle view of the historic city of Palermo, Sicily, with a clear blue sky, buildings and rooftops in the foreground, and mountains in the distance.

Upcoming MSC Cruises from Palermo, Sicily, Italy

13 Results

Taxes and fees included in all prices shown

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A high-angle view of the historic city of Palermo, Sicily, with a clear blue sky, buildings and rooftops in the foreground, and mountains in the distance.

7 nights Westmed From Palermo, Sicily, Italy

Barcelona (Tarragona)

Provence (Marseille)

Florence/Pisa (Livorno)

Aboard

MSC Splendida

From

Palermo, Sicily, Italy

22 Sailings

Jun 11 - Nov 5, 2026

22 Sailings

Jun 11 - Nov 5, 2026

Published prices from

$890

per person*

taxes & fees included

A beautiful image of a narrow, stone-paved street in a medieval Italian village near Livorno, adorned with ivy-covered walls, potted plants, and colorful flowers, giving a feeling of tranquility.

7 nights Westmed From Palermo, Sicily, Italy

Florence/Pisa (Livorno)

Provence (Marseille)

Barcelona (Tarragona)

Aboard

MSC Meraviglia

From

Palermo, Sicily, Italy

18 Sailings

Jun 12 - Oct 9, 2026

18 Sailings

Jun 12 - Oct 9, 2026

Published prices from

$988

per person*

taxes & fees included

A high-angle view of the historic city of Palermo, Sicily, with a clear blue sky, buildings and rooftops in the foreground, and mountains in the distance.

7 nights Westmed From Palermo, Sicily, Italy

Barcelona (Tarragona)

Provence (Marseille)

Aboard

MSC Seaview

From

Palermo, Sicily, Italy

62 Sailings

Jun 15, 2026 - Jan 6, 2028

62 Sailings

Jun 15, 2026 - Jan 6, 2028

Published prices from

$791

per person*

taxes & fees included

A beautiful image of a narrow, stone-paved street in a medieval Italian village near Livorno, adorned with ivy-covered walls, potted plants, and colorful flowers, giving a feeling of tranquility.

4 nights Westmed From Palermo, Sicily, Italy

Florence/Pisa (Livorno)

Provence (Marseille)

Barcelona (Tarragona)

Aboard

MSC Meraviglia

From

Palermo, Sicily, Italy

1 Sailing

Oct 16, 2026

1 Sailing

Oct 16, 2026

Published prices from

$369

per person*

taxes & fees included

A stunning panoramic view of Alicante, Spain, at sunset, with the historic city nestled at the foot of Mount Benacantil and the Santa Bárbara Castle, with the Mediterranean Sea in the distance.

23 nights Caribbean From Palermo, Sicily, Italy

Florence/Pisa (Livorno)

Provence (Marseille)

Barcelona (Tarragona)

Aboard

MSC Meraviglia

From

Palermo, Sicily, Italy

1 Sailing

Oct 16, 2026

1 Sailing

Oct 16, 2026

A scenic panoramic shot from the top of the Rock of Gibraltar, overlooking the city, marina, and the Mediterranean Sea under a bright blue sky.

26 nights Caribbean From Palermo, Sicily, Italy

Florence/Pisa (Livorno)

Provence (Marseille)

Barcelona (Tarragona)

Aboard

MSC Meraviglia

From

Palermo, Sicily, Italy

1 Sailing

Oct 16, 2026

1 Sailing

Oct 16, 2026

Published prices from

$1,863

per person*

taxes & fees included

Mount Vesuvius overlooking Naples Bay.

7 nights Westmed From Palermo, Sicily, Italy

Barcelona (Tarragona)

Provence (Marseille)

Aboard

MSC Euribia

From

Palermo, Sicily, Italy

45 Sailings

Oct 28, 2026 - Mar 22, 2028

45 Sailings

Oct 28, 2026 - Mar 22, 2028

Published prices from

$614

per person*

taxes & fees included

A high-angle view of the historic city of Palermo, Sicily, with a clear blue sky, buildings and rooftops in the foreground, and mountains in the distance.

20 nights South America From Palermo, Sicily, Italy

Barcelona (Tarragona)

Aboard

MSC Splendida

From

Palermo, Sicily, Italy

1 Sailing

Nov 12, 2026

1 Sailing

Nov 12, 2026

Valletta, Malta skyline with illuminated buildings at dusk.

21 nights South America From Palermo, Sicily, Italy

Barcelona (Tarragona)

Aboard

MSC Splendida

From

Palermo, Sicily, Italy

1 Sailing

Nov 12, 2026

1 Sailing

Nov 12, 2026

Published prices from

$1,861

per person*

taxes & fees included

A high-angle view of the historic city of Palermo, Sicily, with a clear blue sky, buildings and rooftops in the foreground, and mountains in the distance.

7 nights Westmed From Palermo, Sicily, Italy

Provence (Marseille)

Aboard

MSC Musica

From

Palermo, Sicily, Italy

28 Sailings

Apr 19 - Oct 25, 2027

28 Sailings

Apr 19 - Oct 25, 2027

Published prices from

$761

per person*

taxes & fees included

A high-angle view of the historic city of Palermo, Sicily, with a clear blue sky, buildings and rooftops in the foreground, and mountains in the distance.

7 nights Westmed From Palermo, Sicily, Italy

Florence/Pisa (Livorno)

Provence (Marseille)

Barcelona (Tarragona)

Aboard

MSC Virtuosa

From

Palermo, Sicily, Italy

29 Sailings

Apr 23 - Nov 5, 2027

29 Sailings

Apr 23 - Nov 5, 2027

Published prices from

$919

per person*

taxes & fees included

A scenic panoramic view of Ilhabela, Brazil, showing a long, sandy beach with turquoise water, a river flowing to the sea, and lush, green mountains under a bright blue sky.

22 nights Westmed From Palermo, Sicily, Italy

Florence/Pisa (Livorno)

Provence (Marseille)

Barcelona (Tarragona)

Aboard

MSC Virtuosa

From

Palermo, Sicily, Italy

1 Sailing

Nov 12, 2027

1 Sailing

Nov 12, 2027

Published prices from

$8,575

per person*

taxes & fees included

A high-angle view of the historic city of Palermo, Sicily, with a clear blue sky, buildings and rooftops in the foreground, and mountains in the distance.

20 nights Westmed From Palermo, Sicily, Italy

Florence/Pisa (Livorno)

Provence (Marseille)

Barcelona (Tarragona)

Aboard

MSC Virtuosa

From

Palermo, Sicily, Italy

1 Sailing

Nov 12, 2027

1 Sailing

Nov 12, 2027

*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.