South America Cruise Deals

Christ the Redeemer statue stands tall over Rio de Janeiro, Brazil, with arms outstretched against a clear blue sky.

Upcoming South America Cruise Deals

Filter

792 Results

Sort

Casa Rosada government building in Buenos Aires.
Save up to 30% on Last Minute Sailings*+ 1 more offer
Seabourn logo

11-night The Great White Continent Cruise

Aboard

Seabourn Venture

From

Buenos Aires, Argentina

Published prices from

$11,643

per person*

taxes & fees included

Casa Rosada government building in Buenos Aires.
Exclusive Onboard Savings, Events & Reduced Fares with Mariner Society*+ 1 more offer
Holland America logo

22-night South America & Antarctica Holiday Cruise

Aboard

Oosterdam

From

Buenos Aires, Argentina

Published prices from

$5,269

per person*

taxes & fees included

Aerial view of Magangué, Colombia, a densely built town with colorful roofs, bordered by a murky river/lake and lush green land, under an overcast sky.
FREE Excursions, Specialty Dining, Wi-Fi & More*+ 1 more offer
AmaWaterways

7-night Wonders of Colombia with 2 Nights Cartagena Pre-Cruise Cruise/Land Package

Aboard

AmaMagdalena

From

Cartagena, Colombia

A beautiful golden-hour shot of a long, sandy beach with waves gently rolling onto the shore, with rolling green hills in the background.
Military Families Save 10%*+ 1 more offer
MSC Cruises logo

7 nights Tropical Brazil

Aboard

MSC Sinfonia

From

Rio de Janeiro, Brazil

Published prices from

$1,112

per person*

taxes & fees included

Rio de Janeiro panoramic with Sugarloaf Mountain and Guanabara Bay.
Military Families Save 10%*+ 1 more offer
MSC Cruises logo

8 nights Brazil Ex Argentina

Aboard

MSC Fantasia

From

Buenos Aires, Argentina

Published prices from

$1,786

per person*

taxes & fees included

Two young elephant seals playing in a small pool of water on a beach covered in seaweed, with icebergs and a dramatic cloudy sky in the background of Drake Passage.
FREE Excursions, Specialized Gear, Dining & More*+ 1 more offer
Viking

18-night Antarctica & South Georgia Island Cruise

Aboard

Viking Octantis

From

Buenos Aires, Argentina

Published prices from

$28,995

per person*

taxes & fees included

Galapagos land iguana on rocks.
75% off 2nd Guest + 3rd, 4th, & 5th Guests Sail FREE + Bonus Savings*+ 2 more offers
Celebrity Cruise Line logo

11-night Quito and Galápagos Inner Loop Cruise/Land Package

Aboard

Celebrity Flora

From

Quito, Ecuador

A scenic aerial shot of Las Bachas, a port of call on Santa Cruz Island in the Galapagos, showcasing a pristine beach with turquoise water.
75% off 2nd Guest + 3rd, 4th, & 5th Guests Sail FREE + Bonus Savings*+ 2 more offers
Celebrity Cruise Line logo

16-night Galápagos Inner Loop and Machu Picchu Cruise/Land Package

Aboard

Celebrity Flora

From

Quito, Ecuador

A relaxed sea lion peacefully sleeping on the unique reddish-brown sand of Isla Rábida in the Galapagos Islands.
75% off 2nd Guest + 3rd, 4th, & 5th Guests Sail FREE + Bonus Savings*+ 2 more offers
Celebrity Cruise Line logo

10-night Quito and Galápagos Inner Loop Cruise/Land Package

Aboard

Celebrity Flora

From

Quito, Ecuador

A scenic aerial shot of the tropical Morro de Sao Paulo beach in Brazil, showing the turquoise Atlantic Ocean, a long stretch of golden sand, and a village with red-roofed houses nestled against a lush green hill.
Military Families Save 10%*+ 1 more offer
MSC Cruises logo

7 nights Northeast Brazil

Aboard

MSC Seaview

From

Santos (São Paulo), Brazil

Published prices from

$668

per person*

taxes & fees included

A tranquil wide-angle shot of a sandy beach along the Gulf of Mexico, with gentle waves rolling onto the shore and a clear blue sky.
Up to $500 FREE Onboard Credit*+ 2 more offers
TCW EXCLUSIVE
Viking

17-night Panama Canal & The Pacific Coast Cruise

Aboard

Viking Sky

From

Fort Lauderdale, Florida

Published prices from

$6,199

per person*

taxes & fees included

A view of the main cruise terminal building at Port Klang in Kuala Lumpur, Malaysia, with its unique architectural style, a long covered walkway, and the sea in front.
Up to $500 FREE Onboard Credit*+ 2 more offers
TCW EXCLUSIVE
Viking

137-night Viking World Cruise

Aboard

Viking Sky

From

Fort Lauderdale, Florida

A vibrant beach scene in Búzios, Brazil, with people swimming and relaxing under white umbrellas on the sand, next to lush green hills and a small white building.
Military Families Save 10%*+ 1 more offer
MSC Cruises logo

4 nights Tropical Brazil

Aboard

MSC Preziosa

From

Santos (São Paulo), Brazil

Published prices from

$859

per person*

taxes & fees included

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.
FREE Butler Service, Gourmet Dining & More*
Silversea logo

9-night Southern Caribbean Cruise

Aboard

Silver Shadow

From

Cartagena, Colombia

Published prices from

$5,900

per person*

taxes & fees included

Rocky beach and palm trees in Barbados.
FREE Butler Service, Gourmet Dining & More*
Silversea logo

16-night Caribbean Cruise

Aboard

Silver Shadow

From

Cartagena, Colombia

An aerial view of the historic walled city of Cartagena, Colombia, showing the vibrant architecture of churches and colonial buildings, with the ocean in the background under a soft morning light.
FREE Excursions, Specialty Dining, Wi-Fi & More*+ 2 more offers
AmaWaterways

7-night Wonders Of Colombia with 3-nights in Panama City Post-Cruise Cruise/Land Package

Aboard

AmaMagdalena

From

Cartagena, Colombia

A close-up of a row of colonial buildings with vibrant, colorful facades in San Basilio de Palenque, Colombia, featuring brightly painted balconies and red-tiled rooftops.
FREE Excursions, Specialty Dining, Wi-Fi & More*+ 1 more offer
AmaWaterways

7-night Wonders of Colombia Cruise

Aboard

AmaMagdalena

From

Cartagena, Colombia

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.
FREE Dining, Onboard Activities & More*+ 1 more offer
Royal Caribbean logo

7-night Southern Caribbean Holiday Cruise

Aboard

Serenade of the Seas

From

Colon, Panama

A large marine iguana sunbathing on a black volcanic rock at Cerro Brujo beach, with a powerful wave crashing in the turquoise waters of the Galapagos Islands.
FREE Butler Service, Gourmet Dining & More*
Silversea logo

7-night Galapagos Islands Cruise

Aboard

Silver Origin

From

Isla San Cristobal, Galapagos Islands

Published prices from

$12,200

per person*

taxes & fees included

Rio de Janeiro panoramic with Sugarloaf Mountain and Guanabara Bay.
Military Families Save 10%*+ 1 more offer
MSC Cruises logo

7 nights Northeast Brazil

Aboard

MSC Armonia

From

Rio de Janeiro, Brazil

Published prices from

$942

per person*

taxes & fees included

A wide shot of the spectacular Petrohué Falls near Puerto Montt, Chile, with turquoise water cascading over volcanic rock, set against the backdrop of the snow-capped Osorno Volcano.
Up to $500 FREE Onboard Credit*+ 2 more offers
TCW EXCLUSIVE
Oceania Cruises

77-night Spanning The Americas Voyage - 2026 World Voyage Segment

Aboard

Vista

From

Los Angeles, California

Published prices from

$23,599

per person*

taxes & fees included

A beautiful scenic shot of the colorful, old-world houses and buildings lining the waterfront of the historic port of Honfleur, France.
Up to $500 FREE Onboard Credit*+ 2 more offers
TCW EXCLUSIVE
Oceania Cruises

197-night World Odyssey Voyage

Aboard

Vista

From

Los Angeles, California

Published prices from

$67,349

per person*

taxes & fees included

A beautiful short-beaked common dolphin, a common species in the waters of Puerto Madryn, Argentina, is captured mid-air leaping from the deep blue, wavy ocean.
75% off 2nd Guest + 3rd, 4th, & 5th Guests Sail FREE + Bonus Savings*+ 2 more offers
Celebrity Cruise Line logo

14-night Patagonia & Argentina Cruise

Aboard

Celebrity Equinox

From

Buenos Aires, Argentina

Published prices from

$1,338

per person*

taxes & fees included

Aerial view of Medellín River and city with mountains in Colombia.
FREE Excursions, Specialty Dining, Wi-Fi & More*+ 1 more offer
AmaWaterways

7-night Magic of Colombia with 3 Nights Medellin Pre-Cruise Cruise/Land Package

Aboard

AmaMelodia

From

Medellín, Colombia

Colorful colonial balconies in Cartagena.
FREE Excursions, Specialty Dining, Wi-Fi & More*+ 1 more offer
AmaWaterways

7-night Magic of Colombia with 3 Nights Medellin Pre-Cruise and 3 Nights Panama City Post-Cruise Cruise/Land Package

Aboard

AmaMelodia

From

Medellín, Colombia

*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.

More to Explore

Cruise Lines

Carnival Cruise Line

Oceania Cruises

Windstar Cruises

Viking River Cruises

Royal Caribbean International

Destinations

Moselle River

Caribbean

Bahamas

European River

India

Ports

Edinburgh (South Queensferry), Scotland

Angkor Thom, Cambodia

Philpots Island, Canada

Montserrat Abbey, Spain

Moab, Utah

Cruise Ships

MSC Seascape

Carnival Magic

AmaCello

AmaSiena

AmaDante