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Panama City skyline from water.

16-night Panama Canal Cruise - Ocean To Ocean From Los Angeles, California

Puerto Vallarta

Aboard

Island Princess

From

Los Angeles, California

3 Sailings

Sep 20, 2026 - Apr 3, 2027

3 Sailings

Sep 20, 2026 - Apr 3, 2027

Published prices from

$1,399

per person*

taxes & fees included

A golden sunset over the beach in Huatulco, Mexico, with footprints in the sand leading towards the shimmering ocean and a warm glow over the water.

16-night Panama Canal - Ocean To Ocean Cruise From Los Angeles, California

Puerto Vallarta

Aboard

Coral Princess

From

Los Angeles, California

1 Sailing

Sep 29, 2026

1 Sailing

Sep 29, 2026

Hollywood sign on hills of Los Angeles.

17-night Panama Canal Eastbound Cruise From Los Angeles, California

Puerto Vallarta

Aboard

Celebrity Summit

From

Los Angeles, California

1 Sailing

Oct 1, 2026

1 Sailing

Oct 1, 2026

Published prices from

$1,780

per person*

taxes & fees included

Immaculate Conception Cathedral in Colon.

15 nights Alaska From Los Angeles, California

Aboard

MSC Poesia

From

Los Angeles, California

1 Sailing

Oct 2, 2026

1 Sailing

Oct 2, 2026

Published prices from

$1,163

per person*

taxes & fees included

Colorful colonial balconies in Cartagena.

16-night Panama Canal Cruise: Mexico, Costa Rica & Colombia From Los Angeles, California

Puerto Caldera (Puntarenas)

Aboard

Norwegian Joy

From

Los Angeles, California

1 Sailing

Oct 7, 2026

1 Sailing

Oct 7, 2026

Published prices from

$2,009

per person*

taxes & fees included

A cruise ship navigating through the Gatun Locks of the Panama Canal, an important navigational route and popular tourist destination.

16-night Panama Canal Cruise: Mexico & Jamaica From Los Angeles, California

Puerto Caldera (Puntarenas)

Aboard

Norwegian Bliss

From

Los Angeles, California

1 Sailing

Oct 13, 2026

1 Sailing

Oct 13, 2026

Published prices from

$1,679

per person*

taxes & fees included

Hollywood sign on hills of Los Angeles.

19-night Panama Canal Cruise: Mexico & Jamaica From Los Angeles, California

Puerto Caldera (Puntarenas)

Aboard

Norwegian Bliss

From

Los Angeles, California

1 Sailing

Oct 13, 2026

1 Sailing

Oct 13, 2026

Published prices from

$1,949

per person*

taxes & fees included

Hollywood sign on hills of Los Angeles.

16-night Panama Canal Cruise - Ocean To Ocean From Los Angeles, California

Puerto Vallarta

Aboard

Crown Princess

From

Los Angeles, California

1 Sailing

Dec 3, 2026

1 Sailing

Dec 3, 2026

Published prices from

$1,301

per person*

taxes & fees included

A cruise ship navigating through the Gatun Locks of the Panama Canal, an important navigational route and popular tourist destination.

16-night Panama Canal Cruise - Ocean To Ocean Holiday From Los Angeles, California

Puerto Vallarta

Aboard

Island Princess

From

Los Angeles, California

1 Sailing

Dec 28, 2026

1 Sailing

Dec 28, 2026

Published prices from

$2,133

per person*

taxes & fees included

A cruise ship navigating through the Gatun Locks of the Panama Canal, an important navigational route and popular tourist destination.

16-night Ultimate Panama Canal Transit Cruise From Los Angeles, California

Puerto Vallarta

Aboard

Seven Seas Grandeur

From

Los Angeles, California

1 Sailing

Jan 24, 2027

1 Sailing

Jan 24, 2027

Published prices from

$13,649

per person*

taxes & fees included

A breathtaking sunset view of the "Monumento al Pescador" fountain in Mazatlán, Mexico, with a silhouette of a man and dolphins against an orange and pink sky.

12-night Sapphire Sojourn Cruise From Los Angeles, California

Aboard

Seven Seas Prestige

From

Los Angeles, California

1 Sailing

Feb 10, 2027

1 Sailing

Feb 10, 2027

Published prices from

$7,549

per person*

taxes & fees included

A stunning view of the Old Port of Marseille, Provence, featuring the basilica of Notre-Dame de la Garde perched on a hill overlooking the harbor filled with many yachts.

30 nights World Cruise From Los Angeles, California

Aboard

MSC Magnifica

From

Los Angeles, California

1 Sailing

Apr 7, 2027

1 Sailing

Apr 7, 2027

Published prices from

$3,889

per person*

taxes & fees included

St. Peter's Basilica, Rome cityscape at sunset.

29 nights World Cruise From Los Angeles, California

Aboard

MSC Magnifica

From

Los Angeles, California

1 Sailing

Apr 7, 2027

1 Sailing

Apr 7, 2027

Published prices from

$3,749

per person*

taxes & fees included

Colorful colonial balconies in Cartagena.

18-night Panama Canal Eastbound Cruise From Los Angeles, California

Puerto Vallarta

Aboard

Celebrity Summit

From

Los Angeles, California

1 Sailing

Sep 18, 2027

1 Sailing

Sep 18, 2027

Published prices from

$3,436

per person*

taxes & fees included

Panama City skyline from water.

18-night Panama Canal - Ocean To Ocean Cruise From Los Angeles, California

Puerto Vallarta

Aboard

Coral Princess

From

Los Angeles, California

1 Sailing

Sep 27, 2027

1 Sailing

Sep 27, 2027

Published prices from

$2,034

per person*

taxes & fees included

A scenic shot of the stunning Seven Mile Beach in Grand Cayman, with a wide, sandy beach, calm turquoise water, and resorts with palm trees under a beautiful blue sky.

17-night Panama Canal from Los Angeles to Miami Cruise: Mexico & Jamaica From Los Angeles, California

Puerto Caldera (Puntarenas)

Aboard

Norwegian Joy

From

Los Angeles, California

1 Sailing

Sep 30, 2027

1 Sailing

Sep 30, 2027

Published prices from

$2,319

per person*

taxes & fees included

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.

16-night Panama Canal - Ocean To Ocean Cruise From Los Angeles, California

Puerto Vallarta

Aboard

Island Princess

From

Los Angeles, California

4 Sailings

Oct 13, 2027 - Apr 3, 2028

4 Sailings

Oct 13, 2027 - Apr 3, 2028

Published prices from

$1,527

per person*

taxes & fees included

A cruise ship navigating through the Gatun Locks of the Panama Canal, an important navigational route and popular tourist destination.

20-night Panama Canal from Los Angeles to New York Cruise: Mexico & Bahamas From Los Angeles, California

Puerto Caldera (Puntarenas)

Aboard

Norwegian Bliss

From

Los Angeles, California

1 Sailing

Oct 19, 2027

1 Sailing

Oct 19, 2027

Published prices from

$2,419

per person*

taxes & fees included

A beautiful beach in Acapulco, Mexico, with thatched-roof umbrellas on the golden sand, facing the turquoise ocean under a clear blue sky.

17-night Panama Canal from Los Angeles to Miami Cruise: Mexico & Bahamas From Los Angeles, California

Puerto Caldera (Puntarenas)

Aboard

Norwegian Bliss

From

Los Angeles, California

1 Sailing

Oct 19, 2027

1 Sailing

Oct 19, 2027

Published prices from

$2,359

per person*

taxes & fees included

A wide-angle landscape shot of the three iconic volcanoes, Agua, Fuego, and Acatenango, in Guatemala, rising above the clouds during a vibrant sunrise, a scenic view near Puerto Quetzal.

16-night Panama Canal - Ocean To Ocean Cruise From Los Angeles, California

Puerto Vallarta

Aboard

Emerald Princess

From

Los Angeles, California

1 Sailing

Oct 24, 2027

1 Sailing

Oct 24, 2027

Published prices from

$1,739

per person*

taxes & fees included

A cruise ship navigating through the Gatun Locks of the Panama Canal, an important navigational route and popular tourist destination.

16-night Panama Canal - Ocean To Ocean Holiday Cruise From Los Angeles, California

Puerto Vallarta

Aboard

Island Princess

From

Los Angeles, California

1 Sailing

Dec 29, 2027

1 Sailing

Dec 29, 2027

Published prices from

$1,744

per person*

taxes & fees included

Hollywood sign on hills of Los Angeles.

Oceania Cruises

44-night Sun, Sand & Seas of Stars Voyage From Los Angeles, California

Aboard

Oceania Sonata

From

Los Angeles, California

1 Sailing

Jan 6, 2028

1 Sailing

Jan 6, 2028

Published prices from

$20,599

per person*

taxes & fees included

A wide-angle landscape shot of the three iconic volcanoes, Agua, Fuego, and Acatenango, in Guatemala, rising above the clouds during a vibrant sunrise, a scenic view near Puerto Quetzal.

Oceania Cruises

16-night Panama Canal Coastlines Voyage From Los Angeles, California

Aboard

Oceania Sonata

From

Los Angeles, California

1 Sailing

Jan 6, 2028

1 Sailing

Jan 6, 2028

Published prices from

$7,899

per person*

taxes & fees included

Lush rainforest and beach in Costa Rica.

15-night Panama Canal from Los Angeles to Miami Cruise: Mexico & Costa Rica From Los Angeles, California

Puerto Caldera (Puntarenas)

Aboard

Norwegian Encore

From

Los Angeles, California

1 Sailing

Jan 9, 2028

1 Sailing

Jan 9, 2028

Published prices from

$2,219

per person*

taxes & fees included

Oranjestad, Aruba harbor with boats and colorful Dutch architecture.

Cunard

14-night 2028 World Voyage Segment: Los Angeles to Miami From Los Angeles, California

Aboard

Queen Elizabeth

From

Los Angeles, California

1 Sailing

Apr 13, 2028

1 Sailing

Apr 13, 2028

Published prices from

$2,899

per person*

taxes & fees included

*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.