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31 Results

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An aerial view of the town of Puerto Varas, Chile, with a prominent red-roofed church in the foreground. The town sits on the shore of a large blue lake, with the snow-capped Osorno Volcano visible in the distance across the water. The sky is bright and clear.
Luxury Accommodations, Exclusive VIP Access & More*+ 2 more offers
Globus

18-Nights South American Odyssey With Amazon

Puerto Varas
Rio de Janeiro
Santiago
Manaus (Amazon River)
Buenos Aires
+3 more

From

Puerto Varas

1 Date

Nov 13, 2026

1 Date

Nov 13, 2026

Published prices from

$9,484

per person*

taxes & fees included

A powerful view of the majestic Iguassu Falls on the Brazilian side, with massive cascades of water, lush green foliage on the rocks, and a vibrant blue sky.
Luxury Accommodations, Exclusive VIP Access & More*+ 2 more offers
Globus

25-Nights South American Odyssey With Amazon & Peru

Lima
Santiago
Buenos Aires
Manaus (Amazon River)
Rio de Janeiro
+7 more

From

Lima

1 Date

Nov 13, 2026

1 Date

Nov 13, 2026

Published prices from

$12,407

per person*

taxes & fees included

Two small squirrel monkeys with light brown and gray fur are perched on a tree branch in the Amazon Jungle of Brazil. One monkey holds a piece of green food, while the other reaches up to it, creating a moment of interaction against a lush, green, out-of-focus background.
Luxury Accommodations, Exclusive VIP Access & More*+ 2 more offers
Globus

11-Nights Independent Brazil & Argentina With Brazil's Amazon - Independent Tour

Manaus (Amazon River)
Iguassu Falls (Brazilian Side)
Rio de Janeiro
Amazon Jungle
Buenos Aires

From

Manaus (Amazon River)

1 Date

Dec 11, 2026

1 Date

Dec 11, 2026

Published prices from

$4,059

per person*

taxes & fees included

Two small squirrel monkeys with light brown and gray fur are perched on a tree branch in the Amazon Jungle of Brazil. One monkey holds a piece of green food, while the other reaches up to it, creating a moment of interaction against a lush, green, out-of-focus background.
Luxury Accommodations, Exclusive VIP Access & More*+ 2 more offers
Globus

9-Nights Independent Rio De Janeiro City Stay With Brazil's Amazon & Buenos Aires - Independent City Stay

Buenos Aires
Rio de Janeiro
Manaus (Amazon River)
Amazon Jungle

From

Buenos Aires

48 Dates

Jan 1 - Dec 3, 2027

48 Dates

Jan 1 - Dec 3, 2027

Published prices from

$3,539

per person*

taxes & fees included

Two small squirrel monkeys with light brown and gray fur are perched on a tree branch in the Amazon Jungle of Brazil. One monkey holds a piece of green food, while the other reaches up to it, creating a moment of interaction against a lush, green, out-of-focus background.
Luxury Accommodations, Exclusive VIP Access & More*+ 2 more offers
Globus

6-Nights Independent Rio De Janeiro City Stay With Brazil's Amazon - Independent City Stay

Rio de Janeiro
Manaus (Amazon River)
Amazon Jungle

From

Rio de Janeiro

48 Dates

Jan 1 - Dec 3, 2027

48 Dates

Jan 1 - Dec 3, 2027

Published prices from

$2,589

per person*

taxes & fees included

Rio de Janeiro panoramic with Sugarloaf Mountain and Guanabara Bay.
Luxury Accommodations, Exclusive VIP Access & More*+ 2 more offers
Globus

8-Nights Independent Rio De Janeiro And Iguassu Falls With Brazil's Amazon - Independent Tour

Rio de Janeiro
Manaus (Amazon River)
Amazon Jungle
Iguassu Falls (Brazilian Side)

From

Rio de Janeiro

45 Dates

Jan 1 - Dec 10, 2027

45 Dates

Jan 1 - Dec 10, 2027

Published prices from

$3,199

per person*

taxes & fees included

Amazonas Theatre in Manaus.
Luxury Accommodations, Exclusive VIP Access & More*+ 2 more offers
Globus

11-Nights Independent Brazil & Argentina With Brazil's Amazon - Independent Tour

Buenos Aires
Rio de Janeiro
Manaus (Amazon River)
Amazon Jungle
Iguassu Falls (Brazilian Side)

From

Buenos Aires

46 Dates

Jan 1 - Dec 3, 2027

46 Dates

Jan 1 - Dec 3, 2027

Published prices from

$4,139

per person*

taxes & fees included

A breathtaking panoramic view of the ancient Inca citadel of Machu Picchu, a UNESCO World Heritage site, showcasing its stone structures and terraced fields amid the Andes Mountains in Peru.
Save up to $600 on 2027 Tours*+ 2 more offers
Cosmos

26-Nights Ultimate South America With Brazil's Amazon & Arequipa & Colca Canyon

Buenos Aires
Lima
Rio de Janeiro
Cuzco
Manaus (Amazon River)
+7 more

From

Buenos Aires

6 Dates

Jan 25 - Nov 1, 2027

6 Dates

Jan 25 - Nov 1, 2027

Published prices from

$8,320

per person*

taxes & fees included

Amazonas Theatre in Manaus.
Save up to $600 on 2027 Tours*+ 2 more offers
Cosmos

22-Nights Ultimate South America With Brazil's Amazon

Buenos Aires
Lima
Rio de Janeiro
Cuzco
Manaus (Amazon River)
+5 more

From

Buenos Aires

4 Dates

Jan 25 - Nov 1, 2027

4 Dates

Jan 25 - Nov 1, 2027

Published prices from

$7,272

per person*

taxes & fees included

Rio de Janeiro panoramic with Sugarloaf Mountain and Guanabara Bay.
Save up to $600 on 2027 Tours*+ 2 more offers
Cosmos

12-Nights The Best Of Brazil & Argentina With Brazil's Amazon

Buenos Aires
Rio de Janeiro
Manaus (Amazon River)
Amazon Jungle
Iguassu Falls (Brazilian Side)

From

Buenos Aires

7 Dates

Jan 27 - Nov 3, 2027

7 Dates

Jan 27 - Nov 3, 2027

Published prices from

$4,412

per person*

taxes & fees included

A breathtaking panoramic view of the ancient Inca citadel of Machu Picchu, a UNESCO World Heritage site, showcasing its stone structures and terraced fields amid the Andes Mountains in Peru.
Save up to $600 on 2027 Tours*+ 2 more offers
Cosmos

23-Nights Brazil, Argentina & Chile Unveiled With Brazil's Amazon & Peru

Buenos Aires
Lima
Rio de Janeiro
Santiago
Cuzco
+5 more

From

Buenos Aires

6 Dates

Feb 24 - Nov 3, 2027

6 Dates

Feb 24 - Nov 3, 2027

Published prices from

$7,800

per person*

taxes & fees included

A powerful view of the majestic Iguassu Falls on the Brazilian side, with massive cascades of water, lush green foliage on the rocks, and a vibrant blue sky.
Save up to $600 on 2027 Tours*+ 2 more offers
Cosmos

19-Nights Brazil, Argentina & Chile Unveiled With Brazil's Amazon & Easter Island

Buenos Aires
Rio de Janeiro
Santiago
Manaus (Amazon River)
Easter Island
+2 more

From

Buenos Aires

4 Dates

Apr 21 - Nov 3, 2027

4 Dates

Apr 21 - Nov 3, 2027

Published prices from

$8,621

per person*

taxes & fees included

Two small squirrel monkeys with light brown and gray fur are perched on a tree branch in the Amazon Jungle of Brazil. One monkey holds a piece of green food, while the other reaches up to it, creating a moment of interaction against a lush, green, out-of-focus background.
Save up to $600 on 2027 Tours*+ 2 more offers
Cosmos

15-Nights Brazil, Argentina & Chile Unveiled With Brazil's Amazon

Buenos Aires
Rio de Janeiro
Santiago
Manaus (Amazon River)
Amazon Jungle

From

Buenos Aires

4 Dates

Apr 21 - Nov 3, 2027

4 Dates

Apr 21 - Nov 3, 2027

Published prices from

$5,441

per person*

taxes & fees included

The ornate Baroque bell towers and domes of a historic stone cathedral in Cuzco, Peru, set against a bright blue sky with clouds.
Luxury Accommodations, Exclusive VIP Access & More*+ 2 more offers
Globus

19-Nights South American Discovery With Brazil's Amazon

Buenos Aires
Lima
Rio de Janeiro
Cuzco
Manaus (Amazon River)
+4 more

From

Buenos Aires

6 Dates

May 6 - Nov 4, 2027

6 Dates

May 6 - Nov 4, 2027

Published prices from

$9,638

per person*

taxes & fees included

Casa Rosada government building in Buenos Aires.
Luxury Accommodations, Exclusive VIP Access & More*+ 2 more offers
Globus

15-Nights South America Getaway With Amazon & Santiago

Buenos Aires
Rio de Janeiro
Santiago
Manaus (Amazon River)
Amazon Jungle

From

Buenos Aires

7 Dates

Jul 16 - Nov 26, 2027

7 Dates

Jul 16 - Nov 26, 2027

Published prices from

$7,591

per person*

taxes & fees included

Casa Rosada government building in Buenos Aires.
Luxury Accommodations, Exclusive VIP Access & More*+ 2 more offers
Globus

12-Nights South America Getaway With Amazon

Buenos Aires
Rio de Janeiro
Manaus (Amazon River)
Amazon Jungle
Iguassu Falls (Brazilian Side)

From

Buenos Aires

5 Dates

Sep 17 - Nov 26, 2027

5 Dates

Sep 17 - Nov 26, 2027

Published prices from

$6,432

per person*

taxes & fees included

Two small squirrel monkeys with light brown and gray fur are perched on a tree branch in the Amazon Jungle of Brazil. One monkey holds a piece of green food, while the other reaches up to it, creating a moment of interaction against a lush, green, out-of-focus background.
Luxury Accommodations, Exclusive VIP Access & More*+ 2 more offers
Globus

18-Nights South America Getaway With Amazon, Santiago & Easter Island

Buenos Aires
Rio de Janeiro
Santiago
Manaus (Amazon River)
Easter Island
+2 more

From

Buenos Aires

4 Dates

Oct 8 - Nov 26, 2027

4 Dates

Oct 8 - Nov 26, 2027

Published prices from

$10,441

per person*

taxes & fees included

Amazonas Theatre in Manaus.
Up to $2,500 off + Stateroom Upgrade*
Globus

11-Nights Independent Brazil & Argentina With Brazil's Amazon - First-Class, Independent

Buenos Aires
Rio de Janeiro
Iguazu Falls (Iguacu Falls)
Manaus (Amazon River)
Amazon Jungle

From

Buenos Aires

9 Dates

Jan 7 - Mar 17, 2028

9 Dates

Jan 7 - Mar 17, 2028

Published prices from

$4,539

per person*

taxes & fees included

Amazonas Theatre in Manaus.
Up to $2,500 off + Stateroom Upgrade*
Globus

8-Nights Independent Rio De Janeiro And Iguassu Falls With Brazil's Amazon - First-Class, Independent

Rio de Janeiro
Manaus (Amazon River)
Amazon Jungle
Iguassu Falls (Brazilian Side)

From

Rio de Janeiro

9 Dates

Jan 7 - Mar 24, 2028

9 Dates

Jan 7 - Mar 24, 2028

Published prices from

$3,259

per person*

taxes & fees included

Two small squirrel monkeys with light brown and gray fur are perched on a tree branch in the Amazon Jungle of Brazil. One monkey holds a piece of green food, while the other reaches up to it, creating a moment of interaction against a lush, green, out-of-focus background.
Up to $2,500 off + Stateroom Upgrade*
Globus

9-Nights Independent Rio De Janeiro City Stay With Brazil's Amazon & Buenos Aires - First-Class, Independent

Buenos Aires
Rio de Janeiro
Manaus (Amazon River)
Amazon Jungle

From

Buenos Aires

10 Dates

Jan 7 - Mar 24, 2028

10 Dates

Jan 7 - Mar 24, 2028

Published prices from

$3,869

per person*

taxes & fees included

Amazonas Theatre in Manaus.
Up to $2,500 off + Stateroom Upgrade*
Globus

6-Nights Independent Rio De Janeiro City Stay With Brazil's Amazon - First-Class, Independent

Rio de Janeiro
Manaus (Amazon River)
Amazon Jungle

From

Rio de Janeiro

10 Dates

Jan 7 - Mar 24, 2028

10 Dates

Jan 7 - Mar 24, 2028

Published prices from

$2,849

per person*

taxes & fees included

"A beautiful panoramic shot of the stunning Iguazu Falls on the border of Argentina and Brazil, with multiple powerful waterfalls cascading down a cliff face and a wooden walkway stretching over the turbulent river in the foreground. "
Up to $2,500 off + Stateroom Upgrade*
Globus

18-Nights South America Getaway With Amazon, Santiago & Easter Island - Classic, First-Class

Buenos Aires
Rio de Janeiro
Santiago
Iguazu Falls (Iguacu Falls)
Manaus (Amazon River)
+3 more

From

Buenos Aires

11 Dates

Jan 14 - Oct 13, 2028

11 Dates

Jan 14 - Oct 13, 2028

Published prices from

$11,172

per person*

taxes & fees included

Two small squirrel monkeys with light brown and gray fur are perched on a tree branch in the Amazon Jungle of Brazil. One monkey holds a piece of green food, while the other reaches up to it, creating a moment of interaction against a lush, green, out-of-focus background.
Up to $2,500 off + Stateroom Upgrade*
Globus

15-Nights South America Getaway With Amazon & Santiago - Classic, First-Class

Buenos Aires
Rio de Janeiro
Santiago
Iguazu Falls (Iguacu Falls)
Manaus (Amazon River)
+2 more

From

Buenos Aires

10 Dates

Jan 14 - Oct 13, 2028

10 Dates

Jan 14 - Oct 13, 2028

Published prices from

$8,092

per person*

taxes & fees included

Two small squirrel monkeys with light brown and gray fur are perched on a tree branch in the Amazon Jungle of Brazil. One monkey holds a piece of green food, while the other reaches up to it, creating a moment of interaction against a lush, green, out-of-focus background.
Up to $2,500 off + Stateroom Upgrade*
Globus

12-Nights South America Getaway With Amazon - Classic, First-Class

Buenos Aires
Rio de Janeiro
Iguazu Falls (Iguacu Falls)
Manaus (Amazon River)
Amazon Jungle

From

Buenos Aires

11 Dates

Jan 14 - Oct 13, 2028

11 Dates

Jan 14 - Oct 13, 2028

Published prices from

$6,955

per person*

taxes & fees included

A panoramic, elevated view of the city of Puno, Peru, with its dense collection of buildings and a prominent, historic church with twin towers and a dome in the foreground. The city is situated on the shore of a vast, calm body of water, with distant hills visible on the far side and a colorful sunset sky above.
Up to $2,500 off + Stateroom Upgrade*
Cosmos

26-Nights Ultimate South America With Brazil's Amazon & Arequipa & Colca Canyon - Value Vacation

Buenos Aires
Lima
Rio de Janeiro
Iguazu Falls (Iguacu Falls)
Cuzco
+8 more

From

Buenos Aires

10 Dates

Jan 24 - Oct 30, 2028

10 Dates

Jan 24 - Oct 30, 2028

Published prices from

$8,868

per person*

taxes & fees included

    • Showing results 1 - 24 of 31

*Rates and offers are per person, in US Dollars, based on double occupancy, capacity controlled, subject to availability and confirmation, and may change without notice. Government taxes and fees are included. Rates and offers are available for select dates and categories only. Additional restrictions may apply. Call 1-800-377-9383 for full terms and conditions.