22-night South America & Antarctica Cruise From Buenos Aires, Argentina

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A breathtaking action shot of a killer whale breaching from the deep blue Antarctic waters, with a massive glacier and icebergs in the background.
Holland America's Oosterdam sailing in Alaska.
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Sailing Feb 1, 2027

Your 22-night South America Cruise at a Glance

Sailings aboard Oosterdam depart from Buenos Aires, Argentina with 16 stops in ports-of-call including Antarctic Experience, Alley Glacier, and Punta Arenas. The Cruise Web can help you find the best deals and stateroom prices on the next sailing February 1, 2027.

Buenos Aires, the vibrant capital of Argentina, is a city full of energy, rich culture, and European-inspired architecture. Before you depart Buenos Aires, Argentina, we can help you plan travel and accommodations for your South America cruise.

Destination

South America

Stops on your South America voyage will include Puerto Madryn on day 5 and Santiago (San Antonio) on day 23. We can help you with excursions and making the most of any itinerary.

Cruise Ship

Oosterdam

Oosterdam, built in 2003 and refurbished in 2019, carries 1,964 passengers with a crew of 817. Ask us about dining options like Lido Market and entertainment like Cantare!

Amazing food and superb service make Holland America one of the longest running cruise lines. We can help you maximize deals on South America cruises aboard Oosterdam or 10 of Holland America’s other ships.