16-night Panama Canal - Ocean To Ocean Cruise From San Francisco, California

Princess Cruises logo

Colorful colonial balconies in Cartagena.
Ruby Princess cruise ship exterior.
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Sailing Aug 28, 2028

from $2,314 per person* taxes and fees included

Your 16-night Mexico Cruise at a Glance

Sailings aboard Ruby Princess depart from San Francisco, California with 7 stops in ports-of-call including Fuerte Amador (Panama City), Cartagena (Colombia), and Puerto Quetzal. The Cruise Web can help you find the best deals and stateroom prices on the next sailing August 28, 2028.

San Francisco, California is a city of steep hills, sweeping views, and unforgettable character—where creativity, culture, and coastline collide. Before you depart San Francisco, California, we can help you plan travel and accommodations for your Mexico cruise.

Destination

Mexico

Stops on your Mexico voyage will include Puerto Quetzal on day 8 and Ft. Lauderdale on day 17. We can help you with excursions and making the most of any itinerary.

Cruise Ship

Ruby Princess

Ruby Princess, built in 2008 and refurbished in 2018, carries 3,080 passengers with a crew of 1,200. Ask us about dining options like 24-hour room service and entertainment like Princess Theater!

Cruise Line

Princess Cruises

Best known for the Pacific Princess on the Love Boat, Princess Cruises has been a leading name in cruising and visits a wide range of destinations. We can help you maximize deals on Mexico cruises aboard Ruby Princess or 16 of Princess’s other ships.